And while many smaller businesses still maintain these kinds of records and prepare invoices using a spreadsheet or word processing application, there are plenty of specialized software apps that let you perform the task quicker, more easily, and with much less effort. In accounting terms, this workflow is part of Accounts Receivable. It also gives you a data path to record all of that data in your other accounting and bookkeeping systems. This software gives you the means to track your sales or services rendered, who was billed, the fees or charges applied, and when payment was received (or when it was supposed to be received but wasn't). This is where billing and invoicing software comes in. Being able to juggle tax information, create receipts, expense accounts, as well as automate follow-up notices, are valuable features for SMBs. For small to midsize businesses (SMBs), the ability to articulate the services rendered as well as the payment options and timing in a professional way is critical to getting paid quicker. ![]() Retail operations live on cash and credit payments, while services-based businesses and freelancers have particular needs and can work with online payment solutions. The type of business you run as well as the clients you have will all factor into your choice of billing and invoicing solution. Other products specialize in helping you keep up on billing and invoicing tasks. This type of software helps you add more electronic payment channels and mobile payment networks that can make paying quicker and easier for your customers. Luckily, great billing and invoicing solutions can remove a lot of the pain in the billing process, giving you more options for receiving payments and speeding up your tasks. This is especially true of smaller business owners or freelance operators. The reality is, if you don't track down payment for a service or product, then your customers most likely won't rush to fork it over on their own. The cliché about the world not beating a path to your door seems to be doubly true when it's regarding people who owe you money. Read our editorial mission (Opens in a new window) & see how we test (Opens in a new window). Since 1982, PCMag has tested and rated thousands of products to help you make better buying decisions. How to Set Up Two-Factor Authentication.How to Record the Screen on Your Windows PC or Mac.How to Convert YouTube Videos to MP3 Files.How to Save Money on Your Cell Phone Bill.How to Free Up Space on Your iPhone or iPad. ![]() How to Block Robotexts and Spam Messages.
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![]() Therefore we evaluated the diagnostic performance of current detection strategies for ROS1-rearrangement in two NSCLC-patient cohorts. ![]() ![]() However, the reliability of such an assay and the comparability of the antibody clones has been debated. To distinguish these rare cases, screening with immunohistochemistry (IHC) for ROS1 protein expression has been suggested. Patients with non-small cell lung cancer (NSCLC) harboring a ROS proto-oncogene 1 (ROS1)-rearrangement respond to treatment with ROS1 inhibitors. Much of this work is devoted to resistance mechanisms and the development of promising new molecules. This review summarizes current knowledge on ROS-1 rearrangement in NSCLCs, including the mechanisms responsible for ROS-1 oncogenicity, epidemiology of ROS-1-positive tumors, methods for detecting rearrangement, phenotypic, histological, and molecular characteristics, and their therapeutic management. More recently developed are ROS-1-targeting TKIs that are active against resistance mechanisms appearing under crizotinib and have better brain penetration. Since 2016, crizotinib has been the first-line reference therapy, with two-thirds of the patients’ tumors responding and progression-free survival lasting ~20 months. It has been demonstrated that ROS-1 is a true oncogenic driver, and tyrosine kinase inhibitors (TKIs) targeting ROS-1 can block tumor growth and provide clinical benefit for the patient. ROS-1 rearrangement is found in 0.9–2.6% of non-small-cell lung cancers (NSCLCs), mostly lung adenocarcinomas, with a significantly higher rate of women, non-smokers, and a tendency to a younger age. The ROS-1 gene plays a major role in the oncogenesis of numerous tumors. ROS1 fusion was more prevalent among younger patients, never‐smokers, and those at advanced node stages. Age, smoking status, and lymph node stage were statistically significantly correlated with ROS1 fusion frequency (all P < 0.05) gender and pathology type were not significantly correlated with ROS1 fusion status after adjusting for smoking status.Īn overall ROS1 fusion frequency of 2.59% was confirmed in this study. Fusion frequency was significantly correlated with age, gender, smoking status (all P 0.05). The average age was 60.89 ± 10.60 years and fusion was detected in 157 (2.59%) patients. In total, 6066 patients with pathologically confirmed NSCLC and ROS1 fusion test results were enrolled. Associations between ROS1 fusion and clinical characteristics were analyzed. The presence of ROS1 fusion was assessed by quantitative real‐time PCR. The study was conducted to investigate the clinicopathological features and prevalence of ROS1 gene fusion in Chinese patients with non‐small cell lung cancer (NSCLC). I called Omnisphere and didn't get a response and I got tired of waiting. I have seen this problem that many people on the net have and no real solution. I have seen people on the net with that problem though, which is similar to mine. zmap, and I have no idea what that is or what happened to that. After one reinstall, I got an issue that involved a. Then, one I reinstalled the program, I get the same error message:Ĭan not load soundsource '.' in directory 'Core Library'. So, I figured that I would just delete everything and go back and reinstall without the updates until I could sort it out. Then I started to add the updates and everything went haywire. I'm a new user of Omnisphere, Trillian ![]() If everything works, you’re good to go!Īlthough they don’t all have conversion tools, these are the best Microsoft Office alternatives. Take a look at the formatting and make sure you can edit the document as you want without graphics or text behaving strangely. Step 4: Word will then convert the document into a Word file and open it. It may take some time, and it may not look exactly like the PDF due to formatting differences. Word will then bring up a notification that lets you know it’s going to convert the PDF to an editable Word document. Step 3: Select the PDF you want to convert, just like opening a Word file. Step 2: Locate the PDF you want to convert using one of the three locations listed under the Personal and Other locations headers: OneDrive, This PC, or Browse. Step 1: Launch Word and click Open listed on the left. After all, other solutions may be more accurate. If you have Acrobat or don’t mind trying a web-based converter, we suggest trying another option if the formatting is unusable. The formatting doesn’t always line up and the text may not be exact. Microsoft Word is a decent alternative to convert PDFs to Word documents - if you have a subscription. ![]() Name your new Word file and save it in your desired location. ![]() Keep in mind that you may need to do some quick reformatting in your new Word document afterward. It doesn't always work, but for most legible text, it's an ideal solution. Step 6: Adobe will automatically run text recognition for any scanned text during this step. Step 5: Click the Export button to finish. Step 4: In both cases, you can click the Cog symbol and change four specific settings: Layout settings, Comments settings, Image settings, and Text recognition settings. ![]() doc format, click the Circle next to Word 97-2003 document instead. Step 3: On the following screen, select Microsoft Word. Linus Tech Tips restored after crypto scam hackĬanva’s new AI tools might replace your video editor It's also a shortcut found under Create and edit on the Tools panel.ĬhatGPT just plugged itself into the internet. Step 2: Select Export PDF, which is listed on the right. Alternatively, if you already have Acrobat open, click the Tools tab along the top. Depending on your preferences, PDF files may automatically open in Acrobat. Step 1: Open the PDF you'd like to convert in Acrobat. You cannot use Acrobat Reader DC to convert PDFs. If you need to make conversions on a regular basis, you'll want to pay for the full version, which runs approximately $15 a month with an annual commitment or as part of an Adobe Creative Cloud package. Note: This trial is designed to prevent you from signing up for it repeatedly, so think of it as a one-time-only option. Adobe currently offers a free, seven-day trial of Adobe Acrobat Document Cloud (DC), which you can use for one-time conversions. However, you'll need the paid version of Acrobat to use this method. Using Acrobat is the best way to make sure the document's format remains as accurate as possible. Here, we'll walk you through a few of the ways you can convert PDFs to Word documents that you can then edit. Originally saved as a PDF, they may prefer to view it in Word rather than Adobe's software. For instance, a potential employer may want to read your resume. However, there may be times when you need that document in another format other than a PDF. I purchased a 700-series in the beginning of August primarily to commute to my business, a 12 mile round trip, 5 days a week for 60 miles a week. Otherwise, the bike is solid, well built, easy to assemble and aesthetically pleasing in appearance. I’m sure I won’t be disappointed in the performance. I only gave the 4 star rating because we’ve not been able to ride them yet. The seat changes are not expensive alterations. I’m disappointed that bike does not have suspension forks but I saw a tip about getting a suspension seat so we might change that out. If that one fits me better, we’ll trade off. My husband likes it so much, we ordered another bike-this time the Core 5. My other bikes have much more, shall we say, “friendly” seats. I’m pretty sure I’ll have to change the seat. ![]() I will say, the bike appears a little big for me even though I got the step through. I haven’t been able to ride it at all due to the weather so I’m unable to comment on that. I saw so many comments about the difficulty of assembling it and that concerned me but my husband was able to put it together with no difficulty at all. Then when the price on the 700 dropped and was so close to the 500, I decided to place the order for that bike instead. ![]() I originally had my eye on the 500 Series. I made up my mind on a price point and then kept checking the sale pricing periodically. I compared ebikes for almost a year and finally decided the Ride 1Up was the one I wanted. Ordering a bicycle in NE OH in the winter time may not be the ideal time but the price became too low to resist. ![]() Other features include enabling keyboard and touchpad support as well as the overall acceleration. You can control the scrolling core features such as framerate and how far down the page will scroll. With that said, the MouseWheel Smooth Scroll plugin doesn’t have too many features. It’s worth mentioning that you can use this plugin even if your theme comes with smooth scroll because the plugin gives you more control over the smooth scroll effects and duration. The MouseWheel Smooth Scroll plugin allows you to easily add smooth scroll to your WordPress website in case your theme doesn’t support this feature out of the box. The plugin has 4,5-star rating and more than 10,000 active installs. The MouseWheel Smooth Scroll plugin is a free plugin that can be downloaded from the official plugin repository. Smooth scrolling is usually used if you have a theme that uses a parallax effect, when you use anchor links to jump to different sections on the page, and when you want to have a smooth scroll effect for your back to top button. Smooth scrolling is especially useful if you have long pages on your website as the smooth scroll makes it easier to digest a lot of content at once. Rather, it will scroll smoothly down to the next page so the users can still see the content they are scrolling past and how much they have scrolled down. Instead, it will scroll a little further than your scrolling point to make the scrolling smoother.Īdditionally, smooth scrolling is useful with keyboard shortcuts because with this feature enabled the page won’t abruptly jump to the next page when users press the Page Down button. The smooth scroll feature can help the user experience on your site as the scrolling won’t suddenly stop when you stop scrolling. This feature was introduced by major applications like Google Chrome to combat the choppy feel of natural scrolling. Smooth scroll refers to the feature that allows visitors to scroll smoothly. What is Smooth Scroll and Why Your Website Needs It On top of that, I’ll also show you two other plugins that add the smooth scroll effect only for certain parts of your website like anchor links and back to top buttons. In today’s post, I’ll explain why some websites have this effect and show you how you can enable it on your website without any coding. If you answered yes, you’re in the right place. Have you ever wondered how on some websites you can scroll smoothly down the page? Moreover, have you ever wanted to have that effect on your site? Learning Python Programming language Computer programming, ruby transparent background PNG clipart size: 500x500px filesize: 37.64KB.Computer Icons Big data Data analysis, automation transparent background PNG clipart size: 500x500px filesize: 28.06KB.Logo WhatsApp Scalable Graphics Icon, Whatsapp logo, telephone call logo transparent background PNG clipart size: 1000x1000px filesize: 39.31KB.WinZip Data compression Computer Software RAR, zipper transparent background PNG clipart size: 1036x1024px filesize: 94.8KB.Web development Computer Icons Computer programming Programmer HTML, Firm transparent background PNG clipart size: 512x512px filesize: 18.81KB.Database Computer Icons Data management, toolkit icon transparent background PNG clipart size: 512x512px filesize: 88.69KB.black laptop computer illustration, Computer programming Web development Computer Software Programming language Theme, coder transparent background PNG clipart size: 8000x5320px filesize: 216.39KB.Cloud Summer, Summer sun and clouds transparent background PNG clipart size: 1024x1024px filesize: 224.46KB.Rainbow Light Color, rainbow transparent background PNG clipart size: 1193x798px filesize: 614.51KB.Debugging Logo Problem solving Computer programming, others transparent background PNG clipart size: 640圆40px filesize: 59.85KB.E logo, SPSS Modeler IBM Data analysis Statistics, ibm transparent background PNG clipart size: 512x512px filesize: 147.91KB. ![]() Wall, Black Crack transparent background PNG clipart size: 1035x1352px filesize: 288.38KB. ![]() blue and yellow logo, Python Logo Clojure JavaScript, 9 transparent background PNG clipart size: 1152x1150px filesize: 146.57KB.blue letter C logo, Logo C++ Programmer, letter C transparent background PNG clipart size: 800圆00px filesize: 9.21KB.Programming language Computer programming Java, programacion transparent background PNG clipart size: 1000x500px filesize: 252.62KB.Whats App application, WhatsApp Logo Computer Icons, whatsapp transparent background PNG clipart size: 1024x1024px filesize: 56.43KB.DevOps Computer Icons Agile software development, others transparent background PNG clipart size: 630圆30px filesize: 13.36KB.C# logo, C# Programming language Computer Icons Computer programming, programming transparent background PNG clipart size: 1600x1600px filesize: 23.13KB.The C++ Programming Language Programmer Computer Icons Computer programming Source code, coding transparent background PNG clipart size: 600圆00px filesize: 11.94KB.Infographic Template Data type Information, variety of programming languages transparent background PNG clipart size: 814x819px filesize: 115.88KB.multicolored streaming template, Computer programming Web development Computer Icons Source code Computer Software, coding transparent background PNG clipart size: 1067x1067px filesize: 24.19KB.Python Logo, Programming Language, Executable, Computer Program, Plex, Data, Software Development Kit, Anaconda transparent background PNG clipart size: 4159x4159px filesize: 384.84KB.blue Google map arrow icon, Computer Icons, location icon transparent background PNG clipart size: 1200x1200px filesize: 26.36KB.Java logo, Java Runtime Environment Computer Icons Java Platform, Standard Edition, java transparent background PNG clipart size: 518x518px filesize: 44.67KB.WinRAR Data compression Computer Software CCleaner, others transparent background PNG clipart size: 630x520px filesize: 255.56KB. ![]()
When feeding, remember that less is best. This water will, in time, become harmful to the fish. Overfeeding, especially in a small goldfish bowl, will cause the water to become cloudy and smelly from the accumulation of decayed food. ![]() You must feed a designated Goldfish Food for best results.īe very careful with your feedings. Over time, feeding tropical fish food to goldfish will seriously affect their health and longevity. It is true that goldfish will eat tropical fish food, but they will reap very little nutritional benefit from it. Tropical fish food is too acidic for their digestive system. Food is absorbed as it travels through their intestines, so it must have a high alkaline content. It is very important to understand that goldfish do not tolerate tropical fish food well. For example, a 2-gallon fish bowl should not house more than two, 2-inch long goldfish. An Aquarium Adventure Fish Specialist can help you select a good specimen.Īs a general rule, you should not keep more than two (2) inches of fish per gallon of water. Feeder goldfish, or “carnival goldfish” as they are sometimes referred, are generally not the fish of choice. You will then need the right, healthy goldfish. This will prevent damage to the gills of the goldfish. Tap water is suitable for them, but it should be “conditioned” to rid it of chlorine or chloramine prior to pouring it into the bowl. Most of the goldfish sold at Aquarium Adventure are pond raised. Typically, goldfish come from waters that are alkaline and slightly hard. ![]() The stress can be very traumatic.įor best results, you should start by filling your goldfish bowl with “aged” or “conditioned water” found in existing aquariums. The long flowing fins and the slow motion of the goldfish make them irresistible targets to many fast fin nipping tropical fish. In addition, goldfish can be threatened by tropical fish. Secondly, goldfish like colder waters than tropical fish. Come visit our store and take a tour!Ī very important fact to remember when caring for goldfish, is that it is not a good idea to keep them with tropical fish. Our experts can answer those really tough questions about installing and maintaining garden ponds.a service the hardware stores cannot provide. We offer everything from do-it-yourself pond equipment and starter sets to full custom installation packages. Aquarium Adventure carries the widest selection of aquariums, fish, corals & plants.ĪBOUT US AQUATIC PROFESSIONALS LOCATIONS TIP SHEETS FRANCHISE ![]() So, even though his long, fantastic tenure as ND basketball coach ended with a whimper here in this 2022-2023 season that saw the Irish go 11-21 overall, 3-17 in ACC play, and one-and-done in the ACC Tournament, what Michael Paul Brey accomplished in his 23 seasons at the helm has been absolutely awesome, and there’s a pretty solid argument he’s the greatest ND men’s basketball coach in at least the modern era. That’s a tough combination of things to do well and to sustain for a long time. Lots of talent development, lots of identifying diamonds in the rough in recruiting, and plenty of unique/innovative strategies and systems are necessary. ![]() So, to find success in a job like that, someone really needs to be a special coach and approach running that program differently. In a sport where kids only need to stay for a year before being allowed to pursue professional aspirations, it’s really hard to convince top-flight talent to spend that one year attending a school like ND in South Bend, Indiana when they could go with a number of other options that come with being the kings of campus in a better geographical location at a program with the resources and talent to compete for a national championship way more regularly. It’s a really tough job in a sport that’s difficult to navigate for even some of the traditional, blue-blood power programs with unlimited resources and fewer academic restrictions, let alone Notre Dame, where that is decidedly not the case. ND is looking for a new head basketball coach right now, but you’ll find more online discussion and reporting and speculation and message-board-meltdown-ing about the recent offensive coordinator, offensive line coach, and special teams coordinator job openings than you’ll find about whom Jack Swarbrick may have already started back-channeling with as the NCAA men’s hoops season ventures into March Madness. There’s no arguing that, and I think it’s safe to say that that hierarchy extends not just to the resources and leeway that football gets more of when compared to hoops, but also to how fans follow and feel about both programs. Notre Dame Fighting Irish men’s basketball has always been, and likely always will be, second fiddle to the football program. d unit : choose EM-dist (or Earth-Moon distance, equal to `3.844*10^8` m).m 2 unit : choose MM (or mass of the Moon, equal to `7.342 × 10^22` kg).m 1 unit : choose ME (or mass of the Earth, equal to `5.972 × 10^24` kg).Unit of F : choose N (Newton) or whatever appropriate unit.Gravitational force F : input x or leave empty (this is the variable to calculate).To evaluate this force with the calculator, enter the following values, Let's calculate the gravitational force between the Earth and the Moon, first with the formula then with the calculator above. G is the universal gravitational constant whose value is,Įxample 1. These forces have the same intensity F equal to,į is the force of attraction between the two bodies in Newton,ĭ is the distance between the two bodies in meter. ![]() ![]() The forces exerted by body 1 on body 2 (`\vecF_12`) and vice versa by body 2 on body 1 (`\vecF_21`) are vector opposite,.According to the universal law of gravitation formulated by Isaac Newton in 1687, two bodies of mass `m_1` and `m_2` spaced at distance d, exert one on the other a force of attraction according to the following laws : |